Mucinous endometrial cancer: Clinical study of the eleven cases

OBJECTIVE: In this study, we analyzed surgico-pathologic factors of mucinous type endometrial carcinoma and examined its frequency of recurrence.
METHODS: In this study, eleven cases, definitely diagnosed as pure mucinous type endometrium carcinoma between January 1993 and May 2013, were reviewed.
RESULTS: Of 1640 women with endometrium carcinoma, 11 (0.67%) of them had a mucinous cell type. Mean age of the study group was 55 years. According to the FIGO 2009, 10 (90.9%) cases were evaluated as stage I and 1 (9.1%) as stage IIIC1. The presence of lymph node metastasis was noticed in only one (12.5%) of eight patients who underwent lymphadenectomy. In this case, metastasis was detected in the pelvic lymph node. Four patients underwent adjuvant therapy as pelvic radiotherapy. Median follow-up time was 50 months (range, 5–84). Recurrence was observed in one (9.1%) patient with stage IIIC1 endometrial cancer in 30 months after primary surgery. The site of recurrence was only in the upper abdominal region.
CONCLUSION: Based on our study, mucinous endometrial carcinoma has good prognostic factors, and long term survival can be achieved surgically alone in patients with stage I.

Müsinöz Endometriyal Kanser: 11 Olgunun Klinik Çalýþmasý

GÝRÝÞ ve AMAÇ: Müsinöz tip endometrial karsinomun cerrahi patolojik faktörlerinin ve nüks sýklýðýnýn araþtýrýlmasý.
YÖNTEM ve GEREÇLER: Ocak 1993 - Mayýs 2013 tarihleri arasýnda saf müsinöz tip endometrium karsinomu tanýsý konan 11 olgu gözden geçirildi.
BULGULAR: Endometrium karsinomalý 1640 kadýndan 11'inde (% 0.67) müsinöz hücre tipi vardý. Çalýþma grubunun yaþ ortalamasý 55 idi. FIGO 2009'a göre, 10 (% 90.9) olgu evre I, 1 olgu (% 9.1) evre IIIC1 olarak deðerlendirildi. Lenf nodu metastazý varlýðý, lenfadenektomi yapýlan 8 hastanýn sadece 1’inde (% 12.5) fark edildi. Bu olguda pelvik lenf nodunda metastaz tespit edildi. Dört hastaya pelvik adjuvan radyoterapi uygulandý. Medyan izlem süresi 50 aydý (aralýk 5-84). Birinci basamak cerrahiden 30 ay sonra evre IIIC1 endometriyal kanserli 1 (% 9.1) hastada nüks görüldü. Yineleme yeri sadece üst batýn bölgesinde idi.
TARTIÞMA ve SONUÇ: Çalýþmamýza göre, müsinöz endometrium karsinomasý iyi prognostik faktörlere sahiptir ve uzun dönem sað kalým, evre I olan hastalarda tek baþýna cerrahi ile baþarýlabilir.