Is it resistant? A case report of splenic endometriosis and review of the literature

Endometriosis is an estrogen dependent benign disease which generally affects woman at childbearing age. Despite its high incidence, pathogenesis of endometriosis is poorly clarified. There are several theories explaining the mechanism of disease such as retrograde menstruation, coelomic metaplasia, vascular and lymphatic metastasis. While endometriosis has been described in many intra and extra abdominal organs including the ovaries, omentum, colon, liver, lungs and brain, parenchymal splenic endometriosis is a rare situation. In recent years, with reported cases, this rare condition came onto the scene. We also wanted to present our case and question the idea of splenic immunity against endometriosis according to current literature. From now on, splenic endometriosis can be thought as differential diagnosis for unidentified lesions of spleen.

Rezistan organ olduðu düþünülen dalakta endometriozis olgusu ve literatür deðerlendirmesi

Endometriozis genellikle doðurgan yaþta kadýnlarý etkileyen östrojen baðýmlý benign bir hastalýktýr. Yüksek insidansa raðmen, endometriozisin patogenezi yeterince açýklanamamýþtýr. Hastalýðýn mekanizmasýný açýklayan çeþitli teoriler bulunmaktadýr; bunlar arasýnda retrograd menstrüasyon, koelomik metaplazi, vasküler ve lenfatik yayýlým sayýlabilir. Endometriozis overler, omentum, kolon, karaciðer, akciðerler ve beyin gibi birçok intraabdominal ve ekstraabdominal organda tanýmlanmýþken, dalakta endometriozis son yýllara kadar bildirilmemiþti. Hatta dalaðýn endometirozise karþý dirençli bir organ olduðu düþünülmekteydi. Bu olgu sunumunda son yýllarda bildirilen vakalarla birlikte kendi vakamýzý literatür eþliðinde deðerlendirmeyi amaçladýk. Bu olgularýn ýþýðýnda dalakta tespit edilen tanýmlanamamýþ lezyonlarda endometriozis ayýrýcý tanýda düþünülmelidir. (NCI-2024-12-5)