Treatment choice in metaplastic breast cancer: A report of 5 cases

Metaplastic breast carcinoma (MBC) is a general term defining a heterogeneous group that includes biphasic lesions, with both malignant epithelial and mesenchymal tissue components. Although its clinical findings are similar to those present in invasive ductal carcinoma, it rarely presents with the findings of inflammatory breast cancer. It is generally seen in the fifth decade. MBC spreads via lymph and blood circulation. Most common distant metastasis areas include lungs and the bone. Although the treatment generally relies on the same principles applied in invasive ductal carcinoma, a more aggressive treatment should be employed in at-risk groups due to higher rates of local recurrence. In this study, we aimed to discuss clinicopathological features and treatment approach in 5 women with MBC.

Metaplastik Meme Kanserinde Tedavi Yaklaþýmý Ne Olmalý? 5 Vakalýk Olgu Sunumu

Metaplastik meme karsinomu (MMK) hem habis epitel hem de mezenþimal doku bileþenleri bulunan bifazik lezyonlarý içeren heterojen bir grubu tanýmlayan genel bir terimdir. Klinik bulgularý invaziv duktal karsinoma benzer olsa da, nadiren inflamatuvar meme karsinomu bulgularý mevcut olabilir. Genellikle beþinci dekant da görülür. Metaplastik meme karsinomu lenf ve kan dolaþýmý ile yayýlýr. En sýk akciðer ve kemiðe uzak metastaz yapar. Tedavi yaklaþýmý genel olarak invaziv duktal karsinomda ayný ilkelere dayanmasýna raðmen, lokal nüks oranlarýnýn yüksek olmasý nedeniyle risk altýndaki gruplarda daha agresif tedavi uygulanmalýdýr. Bu çalýþmada MMK tanýlý beþ kadýn hastanýn klinikopatolojik özelliklerini ve tedavi yaklaþýmýný tartýþmayý amaçladýk.