Evaluation of rhabdomyolysis patients who opted for emergency services

INTRODUCTION: Rhabdomyolysis is a clinical and biochemical syndrome caused by skeletal muscle injury. Our aim was to contribute to the existing data on rhabdomyolysis in our country by evaluating the etiologic, demographic, and clinical features of rhabdomyolysis patients who applied to a tertiary hospital emergency department.
METHODS: We retrospectively evaluated the data of patients who applied to the tertiary hospital emergency department from January 2015 to January 2016. The study population comprised patients admitted to the emergency department of our hospital with creatinine kinase levels above 5000 U/L at admission. The data of all cases that were included in the study were scanned by the researchers using the hospital’s computer-based data recording system. Age, sex, creatine kinase levels, complaints, etiology, whether or not acute renal failure developed, hospitalization and discharge status, and clinic of hospitalization were screened for all patients.
RESULTS: The creatine kinase levels of the patients at admission ranged from 5052 to 59140 U/L [median 7882 U/L (IQR: 7840)]. The most frequent (23.5%) cause of admission was extremity pain. The most common reason (19.6%) in the etiology was exercise. Twenty-one patients (41.1%) were admitted to clinics, and 1 patient (1.9%) died. Acute renal failure was observed in 4 patients (8.8%).
DISCUSSION AND CONCLUSION: Rhabdomyolysis is a clinical syndrome that can be life-threatening owing to muscle destruction. Although it is suspected after a traumatic injury, it should also be considered when other potential symptoms are observed. All clinicians should be aware of its common causes, diagnosis, and treatment options.

Acil servise baþvuran rabdomiyoliz olgularýnýn deðerlendirilmesi

GÝRÝÞ ve AMAÇ: Rabdomiyoliz, iskelet kasý harabiyetine baðlý klinik ve biyokimyasal bir sendromdur. Bu çalýþmada amacýmýz üçüncü basamak bir hastanenin acil servisine baþvuran rabdomiyoliz olgularýnýn etiyolojik, demografik ve klinik özelliklerini inceleyerek ülkemiz rabdomiyoliz verilerine katkýda bulunmaktýr.
YÖNTEM ve GEREÇLER: Çalýþmamýz Ocak 2015 ile Ocak 2016 tarihleri arasýnda üçüncü basamak bir hastanenin acil servisine baþvuran hastalarýn verilerinin retrospektif olarak deðerlendirilmesi ile yapýlmýþtýr. Çalýþma evrenini hastanemiz acil servisine baþvuran ve baþvuru sýrasýnda kreatin kinaz deðerleri 5000 U/L üzerinde olan hastalar oluþturmuþtur. Çalýþmaya dâhil edilecek tüm olgularýn verileri araþtýrmacýlar tarafýndan hastanenin bilgisayar tabanlý veri kayýt sistemi kullanýlarak taranmýþtýr. Olgularýn yaþ ve cinsiyetleri, kreatin kinaz deðerleri, baþvuru þikâyetleri, etyolojileri, akut böbrek yetmezliði geliþip geliþmediði, hastalarýn yatýþ ve taburculuk durumlarý, yatýþ yapýlan hastalarýn yatýþ yapýlan klinikler taranmýþtýr
BULGULAR: Acil servisine baþvuru sýrasýnda kreatin kinaz deðerleri 5000 U/L üzerinde olan 51 hasta çalýþmamýza dâhil edilmiþtir. Hastalarýn baþvurudaki kreatin kinaz deðerleri 5052 ile 59140 U/L arasýnda deðiþmekte olup ortanca 7882 U/L (ÝQR: 7840) olarak bulunmuþtur. En sýk (%23,5) baþvuru sebebi ekstremite aðrýsý idi. Etyolojide en sýk (%19,6) yer alan sebep egzersiz idi. 21 hastanýn (%41,1) kliniklere yatýþýnýn yapýldýðý, 1 hastanýn (%1,9) ise öldüðü tespit edilmiþtir. Hastalarýn 4’ünde (%8,8) akut böbrek yetmezliði geliþtiði gözlenmiþtir.
TARTIÞMA ve SONUÇ: Rabdomiyoliz kas harabiyetine baðlý yaþamý tehdit edebilen klinik bir sendromdur. Her ne kadar travmatik yaralanma sonrasý akla gelse de diðer potansiyel nedenler söz konusu olduðunda da akla getirilmelidir. Bütün klinisyenler ortak nedenlerin, taný ve tedavi seçeneklerinin farkýnda olmalýdýr.