Reaction frequency to the skin prick test of inhalant and food allergens in children

OBJECTIVE: When applied by well-trained personnel, skin prick test (SPT) for a variety of inhalant and/or food allergens is a safe procedure although it may rarely cause systemic reaction. In this article, our aim was to evaluate the reactions after SPTs for the past 6 years in Turkish children having various allergic symptoms brought to our clinic.
METHODS: The results of the SPTs, performed between May 2013 and March 2019, of 12.529 patients whose ages vary from 2 months to 18 years have been retrospectively evaluated.
RESULTS: The average age of the patients who were included in this study was 6.12±4.38 years and 46.4% of them were female. When the patients were categorized according to the diagnosis, it was observed that 4.858 of them with symptoms suggesting asthma; 2.720 of them having symptoms suggesting allergic rhinitis; 1.795 of them having rashes; 906 of them with atopic dermatitis; 352 of them having symptoms suggesting food allergy and the remaining 1.898 with symptoms suggesting various diagnoses. In this study, which reflects our 6-year experience from the results of 12.529 patients, post-SPT reactions have been observed in 9 out of 12.529 patients (0.07%). They were three females and six males. These reactions were observed in 3 eczemas, 2 urticaria, 2 allergic rhinitis, and 2 suggested diagnosis of asthma patients. Their mean age was 5.9±3.5 years. SPT reactions were mostly seen in our five patients having skin disorder (eczema and rashes). The most frequent symptom of vasovagal reaction was syncope, occuring between 1 and 20 min after SPT, in eight of nine patients.
CONCLUSION: During our study, any systemic reaction or anaphylaxis to SPT was not observed. The non-systemic reaction (vasovagal reaction) rate was 7/10.000, similar to the literature.

Çocuklarda Ýnhalan ve Gýda Allerjenleri Deri Prik Testine Karþý Reaksiyon Sýklýðý

Amaç: Nadiren sistemik reaksiyona yol açabilmesine raðmen, deðiþik inhalan ve gýda alerjenleri için yapýlan deri prik testi (DPT) iyi eðitimli personel tarafýndan uygulandýðýnda güvenli bir iþlemdir. Bu makalede, amacýmýz kliniðimize son 6 yýlda deðiþik allerjik semptomlarla getirilen Türk çocuklarýnda deri prik testi sonrasý geliþen reaksiyonlarý geriye dönük deðerlendirmekti.
Yöntemler: 2 ay- 18 yýl arasýnda deðiþen yaþlardaki 12.529 hastanýn Mayýs 2013- Mart 2019 arasýnda yapýlan DPT sonuçlarý geriye dönük deðerlendirilmiþtir. Çalýþmaya katýlan hastalarýn ortalama yaþý 6.12±4.38 ve bunlarýn %46.4’ü kadýndý. Teþhislere göre hastalar gruplandýðýnda; 4.858’inde astýmý, 2.720’inde alerjik riniti, 352’inde besin allerjisini ve 1.898’inde deðiþik alerjik hastalýklarý düþündüren semptomlar, 1.795’inde döküntü ve 906’sýnda atopik dermatit mevcuttu.
Bulgular: 12.529 hastadaki 6 yýllýk deneyimimizi yansýtan bu retsrospektif çalýþmada, DPT sonrasý reaksiyon tüm hastalarýn 9’unda (%0.07) gözlendi. Bu hastalar 3 kadýn ve 6 erkekti. Bu reaksiyonlar 3 egzama, 2 ürtiker, 2 allerjik rinit ve 1 astýmlý hastada gözlendi. Bunlarýn yaþ ortalamasý 5.9±3.5 yaþ idi. Reaksiyonlar en çok deri hastalýðý olan (egzama ve döküntü) beþ hastamýzda görüldü. En sýk, 9 hastanýn 8’inde, görülen vazovagal reaksiyon testten sonraki 1.-20. dakika arasýnda gerçekleþen senkoptu.
Sonuç: Çalýþmamýzda, DPT’ye karþý herhangi bir sistemik reaksiyon veya anafilaksi gözlenmedi. Literatüre uygun þekilde sistemik olmayan reaksiyon (vazovagal reaksiyon) oraný 7/10.000 idi. (NCI-2020-0078.R1)