North Clin Istanb. Ahead of Print: NCI-80688 | DOI: 10.14744/nci.2021.80688

Comparison of syphilis seropositivity between nonimmigrant and immigrant population in Anatolian side of Istanbul Turkey: A five-years of a retrospective study results

Riza Adaleti¹, Nilgun Kansak¹, Muge Aslan¹, Gulcin Balkose², Hande Toptan³, Solen Daldaban Dincer⁴, Sebahat Aksaray^5
1Medical Microbiology Laboratory, Haydarpaþa Numune Training and Research Hospital, University of Health Sciences Istanbul, Turkey
²Medical Microbiology Laboratory, Sýtký Koçman University Training and Research Hospital, Muðla, Turkey
³Department of Medical Microbiology, Sakarya University Faculty of Medicine, Sakarya, Turkey
⁴Medical Microbiology Laboratory, Ümraniye Training and Research Hospital, University of Health Sciences Istanbul,Turkey
⁵Department of Medical Microbiology,University of Health Sciences-Hamidiye Medicine Faculty, Istanbul, Turkey

Objectives
Our study aimed to evaluate the seropositivity for syphilis in nonimmigrantand immigrant populations and compare the results regarding demographic data.
Patients and methods
In accordance with the reverse algorithm, syphilis tests were performed between May 2014 and December 2018 in hospitals in our service zone for syphilis screening or symptomatic disease.
Results
A total of 135.328 nonimmigrantand 6.641 immigrant were screened for syphilis. Seropositivity rates were 1.3% in the nonimmigrant and 3.8% in immigrant groups (p: 0.0001).
There was a statistically significant difference in terms of seropositivity rates between the various age groups in the local group and immigrant groups (except 18- 25 age group)(p<0.05)
Syphilis seropositivity rates were found to be lower in indigenous population than immigrant groups according to the years tested (p: 0.0001)
The seropositivity rates were 2.4% and 3.2% among the males (p: 0.025) and 0.6% and 4.0% among females (p: 0.0001) in nonimmigrant and immigrant groups, respectively. Whereas, 0.6% of pregnant women in the local group and 3.7% of pregnant women in immigrant groups were seropositive for syphilis (p: 0.0001).
Among the HIV positive group, syphilis seropositivity was only observed in the nonimmigrant group with a rate of 23.0% (p: 0.0001).
Conclusions
The antibodies against syphilis were found more frequently in immigrants than nonimmigrant.Among the HIV positive individuals syphilis seropositivity was only observed in the nonimmigrant group.

Keywords: Immigrant, Syphilis seropositivity, HIV positive, Pregnant, Revers algorithm

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Ýstanbul'un Anadolu Yakasýnda Yerli Halk ve Göçmenler Arasýnda Sifiliz Seropozitifliðinin Karþýlaþtýrýlmasý: Beþ Yýllýk Retrospektif Çalýþmanýn Sonuçlarý

Riza Adaleti¹, Nilgun Kansak¹, Muge Aslan¹, Gulcin Balkose², Hande Toptan³, Solen Daldaban Dincer⁴, Sebahat Aksaray^5
1Týbbi Mikrobiyoloji Laboratuvarý, Saðlýk Bilimleri Üniversitesi Haydarpaþa Numune Eðitim ve Araþtýrma Hastanesi, Ýstanbul
²Týbbi Mikrobiyoloji Laboratuvarý, Sýtký Koçman Üniversitesi Eðitim ve Araþtýrma Hastanesi, Muðla
³Sakarya Üniversitesi Týp Fakültesi Týbbi Mikrobiyoloji Anabilim Dalý, Sakarya
⁴Týbbi Mikrobiyoloji Laboratuvarý, Ümraniye Eðitim ve Araþtýrma Hastanesi, Saðlýk Bilimleri Üniversitesi Ýstanbul
⁵Saðlýk Bilimleri Üniversitesi Hamidiye Týp Fakültesi Týbbi Mikrobiyoloji Anabilim Dalý, Ýstanbul

Giriþ
Çalýþmamýzda, demografik veriler ýþýðýnda, yerli halk ve göçmenler arasýnda saptanan sifiliz antikorlarýnýn seropozitiflik oranlarýný deðerlendirmeyi amaçladýk.
Metod
Mayýs 2014, Aralýk 2018 yýllarý arasýnda tarama amacýyla veya semptomatik nedenlerle bölge hastanelerimize baþvuran hastalara, ters algoritmaya uygun olarak, sifiliz testleri yapýlmýþtýr.
Sonuçlar
Toplamda 135.328 yerli ve 3.641 göçmende tarama yapýlmýþtýr. Yerli halk'ta %1.3 ve göçmen gruplarda %3.8 oranýnda sifiliz seropozitifliði saptanmýþtýr(p: 0.0001).
Çeþitli yaþ gruplarýnda, yerli halkta sifiliz seropozitifliði oranlarý göçmenlere göre daha düþük oranda bulunmuþ ve istatistiki anlamada fark saptanmýþtýr(18-25 yaþ grubu hariç)(p<0.05).
Test yapýlan yýllara göre yerli halkta sifiliz seropozitifliði oranlarý, göçmen gruplara göre daha düþük oranda saptanmýþtýr (p: 0.0001).
Yerli halk ve göçmenlerde, seropozitiflik oranlarý sýrasýyla, erkekelerde %2.4 ve %3.2, kadýnlarda %0.6 ve %4 saptanmýþtýr. Buna karþýlýk hamile yerli kadýnlarda %0.6 ve göçmen hamile kadýnlarda %3.7 oranýnda seropozitiflik saptanmýþtýr(p: 0.0001)
HIV pozitif grupta, göçmenlerde sifiliz seropozitifliði saptanmamýþ, yerli halk'ta %23 oranýnda saptanmýþtýr(p: 0.0001).
Sonuç
Sifiliz antikorlarý göçmenlerde yerli halk'a göre daha yüksek oranda saptanmýþtýr. HIV pozitif olanlarda sadece yerli halk'ta sifiliz seropozitifliði saptanmýþtýr. (NCI-2021-2-36/R1)

Anahtar Kelimeler: Göçmen, Sifiliz seropozitifliði, HIV pozitifliði, Hamile, Ters algoritma

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